University of Ottawa
Impact of a CMV-induced NK cell subset in cancer therapy
Host and virus interactions have been established over millions of years of evolution, exhibiting multifaceted consequences. Notably, some interactions are uniquely advantageous to hosts. A recently identified subset of long-lasting Natural Killer (NK) cells that develop post-cytomegalovirus (CMV) infection appears to confer enhanced protective immunity against cancer. Intrigued by this new discovery, we propose to investigate the roles of this subset of NK cells in cancer.