University Health Network
Real-Time Monitoring of Leukemic Stem Cells in the Bone Marrow
Acute myeloid leukemia (AML) arises in the bone marrow, but we know little about how cells enter, live and exit the bone marrow. A better understanding of AML behavior will help optimize the delivery of emerging immunotherapies and improve outcomes. We will use imaging methods to answer these questions in mouse models of AML to inform the design of future immunotherapy-based AML trials in patients at high risk of relapse.