The signs and symptoms of acute lymphoblastic leukemia (ALL) are common to other, less serious illnesses. However, if you're troubled by any of the following symptoms, see your doctor:

• Aches in the arms, legs or back
• Black-and-blue marks (bruises) for no clear reason
• Enlarged lymph nodes
• Fever without an obvious cause or a lasting, low-grade fever
• Headaches
• Pale skin
• Pinhead-size red spots under the skin (called petechiae)
• Prolonged bleeding from minor cuts
• Shortness of breath during normal physical activity
• Tiredness or no energy
• Vomiting
• Unexplained weight loss