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Acute myeloid leukemia on a particular cellular energy pathway for growth and viability
MEIS1 is a protein that controls gene expression. Overexpression of MEIS1 is involved in many blood cancers including leukemias.
The roles of specific gene alterations in patients’ leukemic cells are difficult to study because of many other mutations typically also present.
Leukemia impacts and affects thousands of Canadian families.
Acute myeloid leukemia is an aggressive type of blood cancer that kills over 1,000 people every year in Canada.
We study how mRNAs in cancer cells are modified by a mechanism called m6A methylation, and how such modifications contribute to the origin and progression of cancer.
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